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기초의학

해부학교실

제주대학교 의학전문대학원/의과대학에 오신 것을 환영합니다.

글자크게 글자작게 프린트

해부학교실

해부학교실은 의사가 되는데 있어 가장 중요한 인체의 구조에 관한 교육과 콩판질환, 대장/콩팥암, 그리고 미세먼지 독성에 관한 연구를 수행하고 있다. 본 교실은 인체 구조의 특징과 기능에 관한 기초 지식을 교육하는 국소해부학, 인체의 골격유지에 근간인 뼈대에 관한 지식을 교육하는 골학, 그리고 신경계 질환을 이해하는데 필수적인 신경계의 구조와 기능에 대한 기초 지식을 교육하는 신경해부학을 강의와 실습을 통해 가르치고 있다. 또한, 최신 경향의 형태학적/분자세포생물학적 연구기법과 다양한 유전자 조절 생쥐/세포를 활용하여 섬유화 발생 원인, 항암제 내성 암세포에 대한 효과적 치료법, 미세먼지에 의한 세포죽음 메커니즘을 연구하는데 주력하고 있다

 

 

윤상필 교수

  • 세부전공맨눈해부학
  • 연구실의학전문대학원 423호
  • 전화/국제전화064-754-3823/064-754-3823
  • 이메일spyoon@jejunu.ac.kr
  • 홈페이지
윤상필 경력 및 논문
경력 및 논문
학력 1997. 조선대학교 의학사
1999. 조선대학교 의학석사
2005. 조선대학교 의학박사
주요경력 2004. 12 ~ 2010. 2. 서남대학교 의과대학 해부학교실
2005. 9. ~ 2010. 2. 서남대학교 의과대학 기초의학과장
2007. 9. ~ 현재. 대한해부학회 이사
2009. 1. ~ 현재. ‘Islets' 편집심사위원
2010. 3. ~ 현재. 대한해부학회 학술위원
주요논문 1. Yoon, Sang Pil; Kim, Hyeon Ho; Kim, Jeeho; Park, Ra Young; Ohn, Takbum. Regulation of Cellular RNA Nano-Particle Assembly by Splicing Factor SRp20. Journal of Nanoscience and Nanotechnology, January 2013 , pp. 184-187(4)

2. Pham Thi Thu Huong, Min Young Lee, Kun Yeong Lee, In Youp Chang, Seog Ki Lee, Sang Pil Yoon, Dong-Cheol Lee, and Young Jin Jeon. Synergistic Induction of iNOS by IFN-γ and Glycoprotein Isolated from Dioscorea batatas. Korean J Physiol Pharmacol. 2012 December; 16(6): 431?436.

3. Chang IY, Yoon SP. The changes of calretinin immunoreactivity in paraquat-induced nephrotoxic rats. Acta Histochem. 2012 Dec;114(8):836-41

4. Kim JN, Chang IY, Kim JH, Kim JW, Park KS, Kim HI, Yoon SP. The role of apurinic/apyrimidinic endonuclease on the progression of streptozotocin-induced diabetic nephropathy in rats. Acta Histochem. 2012 Nov;114(7):647-52.

5. Piao C, Youn CK, Jin M, Yoon SP, Chang IY, Lee JH, You HJ. MEK2 regulates ribonucleotide reductase activity through functional interaction with ribonucleotide reductase small subunit p53R2. Cell Cycle. 2012 Sep 1;11(17):3237-49.

6. Hyun CL, Park HS, Shin HJ, Yoon SP. Hypoplasia of left vertebral artery with intimal fibromuscular dysplasia in a Korean woman. J Korean Med Sci. 2012 Jul;27(7):811-3.

7. Joo Oh H, Ko YK, Cho SS, Yoon SP. A cadaveric study of needle insertion at PC6 in eight wrists of four subjects and an understanding of the anatomy. Acupunct Med. 2012 Mar;30(1):44-6.

8. Chang IY, Ohn T, Ko GS, Yoon Y, Kim JW, Yoon SP. Immunolocalization of steroidogenic acute regulatory protein-related lipid transfer (START) domain-containing proteins in the developing cerebellum of normal and hypothyroid rats. J Chem Neuroanat. 2012 Jan;43(1):28-33.

9. Kim JN, Lee HS, Ryu SH, Kim YS, Moon JS, Kim CD, Chang IY, Yoon SP. Heat shock proteins and autophagy in rats with cerulein-induced acute pancreatitis. Gut Liver. 2011 Dec;5(4):513-20.

10. Kang KY, Kim JN, Chang IY, Park SH, Yoon SP. Calretinin immunoreactivity in normal and carbon tetrachloride-induced nephrotoxic rats. Acta Histochem. 2011 Nov;113(7):712-6.

11. Yoo SJ, Ku MJ, Cho SS, Yoon SP. A case of the inferior mesenteric artery arising from the superior mesenteric artery in a Korean woman. J Korean Med Sci. 2011 Oct;26(10):1382-5.

12. Yoon SP, Han MS, Kim JW, Chang IY, Kim HL, Chung JH, Shin BC. Protective effects of chitosan oligosaccharide on paraquat-induced nephrotoxicity in rats. Food Chem Toxicol. 2011 Aug;49(8):1828-33.

13. Chang IY, Kim JN, Jun JY, You HJ, Jeon YJ, Park KS, Yoon SP. Repression of apurinic/apyrimidinic endonuclease by p53-dependent apoptosis in hydronephrosis-induced rat kidney. Free Radic Res. 2011 Jun;45(6):728-34.

14. Chang IY, Jeon YJ, Jung SM, Jang YH, Ahn JB, Park KS, Yoon SP. Does the StarD6 mark the same as the StAR in the nervous system? J Chem Neuroanat. 2010 Nov;40(3):239-42.

15. Chang IY, Kim JH, Park KH, Yoon SP. Experimental varicocele induces p53-dependent germ cell apoptosis through activation of γ-H2AX. Urol Int. 2010;85(2):216-20.

16. Yoon SP. Insights into the Possible Mechanism of Cyclosporine-Induced Chronic Nephrotoxicity; Arteriolopathy. Nephro-Urology Monthly. 2012 March; 4(2): 489-490.

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김진우 부교수

  • 세부전공

    해부학, 콩팥질환연구

  • 연구실의학전문대학원 M415
  • 전화/국제전화064-754-8181/064-754-8181
  • 이메일jinu.kim@jejunu.ac.kr
  • 홈페이지
김진우 경력 및 논문
경력 및 논문
학력

경북대학교 의학과 의학박사 (해부학교실)
경북대학교 의학과 의학석사 (해부학교실)
경북대학교 이학사

주요경력

2013. 08. ~ present 제주대학교 의학전문대학원 조교수
2010. 08. ~ 2013. 08. University of Nebraska Medical Center, 박사후연구원
2010. 03. ~ 2010. 07. Columbia University, 박사후연구원

주요논문

1) Poly(ADP-ribose) polymerase activation induces high mobility group box 1 release from proximal tubular cells during cisplatin nephrotoxicity. Physiol Res. 65:333-40, 2016.
2) Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule epithelial cells. Anat Cell Biol. 49:79-87, 2016.
3) Cisplatin induces primary necrosis through poly(ADP-ribose) polymerase 1 activation in kidney proximal tubular cells. Anat Cell Biol. 48:66-74, 2015.
4) High-throughput 16S rRNA gene sequencing reveals alterations of mouse intestinal microbiota after radiotherapy. Anaerobe. 33:1-7, 2015.
5) TIGAR regulates glycolysis in ischemic kidney proximal tubules. Am J Physiol Renal Physiol. 308(4):F298-308, 2015.
6) Poly(ADP-ribose) polymerase 1 activation links ischemic acute kidney injury to interstitial fibrosis. J Physiol Sci. 65:105-11, 2015.
7) Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy. Am J Physiol Renal Physiol. 308(2):F131-9, 2015.
8) Renal denervation prevents long-term sequelae of ischemic renal injury. Kidney Int. 87:350-8, 2015.
9) Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation. Am J Physiol Renal Physiol. 307:F971-80, 2014.
10) Mechanical stretch induces angiotensinogen expression through PARP1 activation in kidney proximal tubular cells. In Vitro Cell Dev Biol Anim. 51:72-8, 2015.
11) Renal nerves drive interstitial fibrogenesis in obstructive nephropathy. J Am Soc Nephrol. 24:229-242, 2013.
12) Poly(ADP-ribose) polymerase 1 activation is required for cisplatin nephrotoxicity. Kidney Int. 82:193-203, 2012.
13) Intra-renal slow cell-cycle cells contribute to the restoration of kidney tubules injuried by ischemia/reperfusion. Anat Cell Biol. 44:186-193, 2011.
14) Loss of poly(ADP-ribose) polymerase 1 attenuates renal fibrosis and inflammation during unilateral ureteral obstruction. Am J Physiol Renal Physiol. 301:F450-F459, 2011.
15) Protective role of cytosolic NADP+-dependent isocitrate dehydrogenase, IDH1, in ischemic preconditioned kidney in mice. Free Radic Res 45:759-766, 2011.
16) Omi/HtrA2 protease is associated with tubular cell apoptosis and fibrosis induced by unilateral obstruction. Am J Physiol Renal Physiol. 298:F1332-F1340, 2010.
17) Reactive oxygen species differently regulate renal tubular epithelial and interstitial cell proliferation after ischemia and reperfusion injury. Am J Physiol Renal Physiol. 298:F1118-1129, 2010.
18) Reactive oxygen species generated by renal ischemia and reperfusion trigger protection against subsequent renal ischemia and reperfusion injury in mice. Am J Physiol Renal Physiol. 298:F158-F166, 2010.
19) Reactive oxygen species/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice. Am J Physiol Renal Physiol. 297:F461-F470, 2009.
20) Increased superoxide formation induced by irradiation preconditioning triggers kidney resistance to ischemia-reperfusion injury in mice. Am J Physiol Renal Physiol. 296:F1202-F1211, 2009.
21) Role of cytosolic NADP-dependent isocitrate dehydrogenase in ischemia-reperfusion injury in mouse kidney. Am J Physiol Renal Physiol. 296:F622-F633, 2009.
22) Kidney tubular cell regeneration starts in the deep cortex after ischemia. Korean J Nephrol. 27:536-544, 2008.
23) Locations of slow-cycling cells, adult stem cells, in the organs of adult mouse. Anat Cell Biol. 40:347-357, 2007.
24) Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase. J Biol Chem. 281(29):20349-56, 2006.

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